Death Spiral or Ascending Helix

Different amino acid sequences have different propensities for forming ? helical structure. Methionine, alanine, leucine uncharged, glutamate, and lysine (“MALEK” in the amino acid 1 letter codes) all have especially high helix forming propensities, whereas proline and glycine have poor helix forming propensities. Proline either breaks or kinks a helix, Read More